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The Actionable SNP Cheat-Sheet

The genetic variants that actually change what to take and eat — each one cited to a real study. One page. Free. No email required.

Download the free PDF → No signup. Yours to keep and share.

It's the same honesty rule as the rest of Curaen: if a recommendation can't be tied to a named study, it isn't on the sheet. Use it as a quick reference — then see your own results for free.

What's inside

MTHFR · rs1801133
Prefer L-methylfolate (5-MTHF) over folic acid. It's pre-activated, so MTHFR's slow step doesn't matter.
 CYP1A2 · rs762551
Slow metaboliser? Keep caffeine to the morning and cap the total — that's the lever that actually works.
 FADS1 · rs174546
Less-efficient converters benefit most from preformed EPA/DHA (fish oil, or algae oil if vegan).
 PEMT · rs7946
Prioritise choline-rich foods (eggs, liver) or a choline supplement if your intake is low.
 MTRR · rs1801394
Favor methylcobalamin (the active B12 form) over cheap cyanocobalamin if you supplement.
 APOA5 · rs662799
Preformed omega-3 (EPA/DHA) is a proven triglyceride lever — more valuable for your genotype.
 TCF7L2 · rs7903146
Diet and post-meal movement target the exact mechanism — the highest-leverage levers.
 LCT · rs4988235
Non-persistent? A lactase enzyme with dairy, or lactose-free products, solves most of it.
 GC · rs7041
Test 25(OH)D rather than guessing — genetics raise risk, but your number is what counts.
 CYP2R1 · rs10741657
Check 25(OH)D — genetics raise risk, your blood level is the truth.
 TMPRSS6 · rs855791
Don't supplement iron on genetics alone — check ferritin + iron labs first.
 HFE · rs1800562
Default to avoiding iron supplements unless labs say otherwise.
 G6PD · rs1050828
Keep vitamin C to dietary/RDA amounts — skip the megadoses and IV vitamin C.
 ALDH2 · rs671
If you flush, the dependable move is to limit or skip alcohol — there's no supplement workaround.
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